Table 1.

Statistical comparison of receptor expression in 2- and 4-month-old C57BL6 and CBA/CaOlaHsd mice

Receptor	Area	C57BL/6	CBA/CaOlaHsd	P	N
2 months
GluN2A	PPC	21.11 ± 1.74	17.28 ± 1.01	<0.001	6
	VC	19.77 ± 1.31	13.66 ± 1.05	<0.01	6
	AuC	19.66 ± 1.73	13.84 ± 0.87	<0.01	6
mGlu2/3	PPC	33.10 ± 2.51	26.09 ± 2.35	<0.05	6
	VC	33.68 ± 2.79	24.44 ± 1.77	<0.01	6
mGlu5	CA4	97.97 ± 2.43	83.71 ± 6.17	<0.05	5
GABA-B	AuC	28.40 ± 1.74	20.42 ± 1.55	<0.05	6
	CA1	31.34 ± 2.04	20.72 ± 1.40	<0.01	6
4 months
GluN2A	PiC	21.57 ± 1.15	16.75 ± 1.52	<0.05	6
	SC	22.52 ± 1.08	17.49 ± 1.36	<0.05	6
GluN2B	PiC	32.78 ± 2.71	12.27 ± 1.82	<0.001	5
	SC	43.31 ± 2.15	20.08 ± 1.76	<0.001	5
	PPC	46.81 ± 4.27	26.93 ± 1.94	<0.001	5
	VC	39.56 ± 3.58	23.86 ± 1.35	<0.001	5
	AuC	37.38 ± 3.17	20.03 ± 1.71	<0.001	5
	DG	23.12 ± 2.19	11.97 ± 1.30	<0.01	5
	CA1	32.56 ± 2.73	23.28 ± 1.28	<0.05	5
	CA3	31.64 ± 1.98	19.81 ± 1.80	<0.01	5
	CA4	21.89 ± 2.52	10.25 ± 1.48	<0.01	5
mGlu1	SC	39.68 ± 1.52	31.84 ± 1.47	<0.01	5
	AuC	41.96 ± 1.62	34.44 ± 2.25	<0.05
mGlu2/3	PiC	30.96 ± 1.57	24.72 ± 1.24	<0.01	5
	AuC	36.74 ± 1.68	31.07 ± 1.51	<0.05	5
	DG	40.21 ± 2.22	34.68 ± 1.41	<0.05	5
	CA1	16.54 ± 1.73	10.20 ± 0.47	<0.01	5
	CA3	19.87 ± 1.91	12.31 ± 0.98	<0.01	5
	CA4	29.46 ± 3.61	21.52 ± 0.86	<0.001	5
GABA-A	PiC	64.34 ± 4.59	84.58 ± 6.06	<0.05	6
	SC	76.59 ± 5.44	104.76 ± 6.06	<0.01	6
	AuC	78.95 ± 7.88	101.36 ± 5.63	<0.05	6
	DG	79.36 ± 2.87	99.29 ± 4.72	<0.05	6
GABA-B	DG	28.86 ± 1.76	44.06 ± 3.17	<0.001	6
	CA3	31.80 ± 1.15	43.85 ± 3.68	<0.001	6
	CA4	32.50 ± 1.64	49.87 ± 3.85	<0.001	6

Note: The following regions were examined: AuC, PiC, SC, PPC, VC, DG, CA1 region, CA3 region, and CA4 region. Values shown correspond to the mean optical density ± standard error of the mean. “P” indicates the P values obtained in statistical comparisons between C57BL/6 and CBA/CaOlaHsd mice at 2 months (N = 6 each) and 4 months (N = 6 for C57BL/6, N = 5 for CBA/CaOlaHsd mice). “N” indicates the number of animals used in the comparisons.