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. 2020 Jun 10;8:574. doi: 10.3389/fbioe.2020.00574

Figure 3.

Figure 3

Simulating a syntrophic batch co-culture. Propionate is utilized by S. fumaroxidans and converted to acetate, CO2, and H2. M. hungatei then converts CO2 and H2 to CH4. Both Matlab's ode15s ODE solver (lines) and μbialSim's augmented forward Euler method (symbols, every 15th data point is plotted) lead to similar results. As H2 is faster consumed than produced, the time step size gets frequently reduced, most notably just prior to the depletion of propionate after which growth of both populations ceases.