Table 1.

Parameter values and initial conditions used throughout section 6, unless stated otherwise.

Parameters	Interpretation	Value
$x_1^0$	Initial sensitive population	10−2
$x_2^0$	Initial resistant population	0
α	Induced resistance rate due to the presence of the drug	10−2
d	Drug cytotoxicity parameter	1
ϵ	Drug-independent resistance rate	10−6
pr	Resistant growth fraction	0.2
t0	Initial time	0
M	Maximum drug dosage	5
Vc	Tumor volume defining treatment failure	0.9