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. 2020 Jun 11;11:716. doi: 10.3389/fimmu.2020.00716

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Copyright © 2020 Stoler, Freytag, Orak, Unterwalder, Henning, Heim, von Bernuth, Krüger, Winkler, Eschenhagen, Seipelt, Mall, Foell, Kessel, Wittkowski and Kallinich.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Spontaneous alteration of CD62L and CD11b expressions on neutrophils derived from MEFV mutation carriers and controls. Isolated neutrophils from healthy controls (filled circles, n = 6), healthy heterozygous MEFV mutation carriers (filled triangles, n = 6), FMF patients with compound heterozygous or homozygous mutations (open circles, n = 10), and patients with chronic inflammatory as well as infectious diseases (open triangles, n = 24) were cultured without stimulation. Geometric mean fluorescence intensity of CD62L (A) and CD11b (B) expression was measured at the indicated time points by flow cytometry. Values are given as mean and interquartile ranges.