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. 2020 Jun 19;11:359. doi: 10.3389/fendo.2020.00359

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Copyright © 2020 Hou, He, Ma, Yang, Xu, Lam, Shui, Yang, Zhang, Qiang and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sphingolipids were significantly altered in the diabetic kidney cortex. Total content of sphingolipid classes (A) and specific species of Gb3 (B), glucosylceramide (GluCer) (C), galactosylceramide (GalCer) (D), and monosialo-dihexosyl gangliosides (GM3) (E) were analyzed. Data are presented as means ± SEM, n = 6 per group; *P < 0.05, **P < 0.01, ***P < 0.001.