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The EGFR-KDD is an oncogenic EGFR alteration. (A) The Integrative Genomics Viewer snapshot of paired NGS reads of tumor and matched blood. (B) Schematic representation of EGFR-KDD depicting the genetic and protein domain structures. ECD, extracellular domain; TM, transmembrane domain; KD1, first kinase domain; KD2, second kinase domain; C-term, carboxyl terminus. Blue, EGFR exons 18–25 #1; orange, EGFR exons 18–25 #2.
