Figure 3.

Hematopoietic cells constitute a major source of IL-10 production during T. brucei infection. (A) Survival of the chimeric mice 8 weeks post-transplantation as well as IL-10-deficient mice following T. brucei infection i.p., where the median survival (MS) of each group is indicated in days. (B) Cytokine levels were measured by ELISA in plasma of infected chimeric and IL-10-deficient mice 8 days p.i. Data are represented as mean of at least 4 mice per group ± SEM, where *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, and are representative of 2 independent experiments. The dashed line represents the detection limit.