Table 3.
Rating and temperamental profile of MDD and BD patients.
| Study subjects (n = 131) | MDD (n = 78) | BD (n = 53, of whom BD-I = 24; BD-II = 29) | t or χ2 (df) | p |
|---|---|---|---|---|
| Essential ratings | ||||
| HAM-D-17 total score, (mean ± sd) | 19.63 ± 6.19 | 19.55 ± 5.33 | −.078 (129) | .334 |
| YMRS item 2, “increased psychomotor activity” n (%) | 3 (3.85) | 42 (79.25) | 10.935 (3) | .012 |
| YMRS item 3, “hypersexuality” n (%) | 1 (1.28) | 7 (13.21) | 7.827 (1) | .005 |
| YMRS item 5, “irritable mood” n (%) | 29 (31.18) | 30 (56.6) | 8.082 (3) | .044 |
| YMRS item 7, “distractibility” n (%) | 10 (12.82) | 14 (26.42) | 11.020 (2) | .004 |
| TEMPS-A-110 domains for affective temperaments | ||||
| Depressive temperament domain score, range 1–21 (mean ± sd) | 10.14 ± 4.04 | 10.58 ± 3.78 | .568 (102) | .571 |
| Cyclothymic temperament score, range 1–21 (mean ± sd) | 6.64 ± 4.41 | 8.91 ± 4.44 | 2.590 (102) | .011 |
| Hyperthymic temperament, score 1–21 (mean ± sd) |
3.69 ± 3.21 | 5 ± 4.83 | 1.653 (102) | .101 |
| Irritable temperament score, range 1–21 (mean ± sd) | 4.08 ± 3.29 | 6.47 ± 4.37 | 3.170 (102) | .002 |
| Anxious temperament score, range 1–21 (mean ± sd) | 12.22 ± 6.2 | 12.22 ± 5.16 | .002 (102) | .999 |
Statistically significant difference in bold or p ≤.05.
MDD, major depressive disorder; BD, bipolar disorder; HAM-D, Hamilton Depression Scale; YMRS, Young Mania Rating Scale; TEMPS, Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-auto-questionnaire 110-item version.
Selected items of the YMRS emphasized herein as they represent the “overlapping” mixed features not accounted by the DSM-5 for the diagnosis of the “with mixed features” specifier of MDE.