Figure 1.

Arid1a expression is downregulated in retinal ganglion cells (RGCs) after optic nerve crush (ONC). (A) Retinal sections from C57BL/6 mice of different time points post-crush were collected and stained with Tuj1 (red), and ARID1A (green). Scale bar: 20 μm. (B) Quantification of relative fluorescence intensity of ARID1A staining in RGCs. Uninjured was used for normalization, for 1 dpc, ns, no significance; for 3 dpc, **p < 0.01; for 7 dpc, *p < 0.05. RGCs were analyzed from at least eight non-adjacent retinal sections for each animal, from three mice per group.