Table 4.
Association of socioeconomic deprivation and observed survival for subgroups according to received treatment.
| Subgroup | Events [N (%)] | Deprivation quintile [Hazard ration (95% confidence interval)]a | 5-year survival (standard error)b | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Q1(least deprived) | Q2 | Q3 | Q4 | Q5(most deprived) | Q1 (%) | Q5 (%) | Q5–Q1 (% units) | ||
| Stage I | 2,706 (31.1) | 1.00 (ref) | 0.79 (0.70–0.90) | 0.99 (0.87–1.13) | 1.14 (1.01–1.30) | 1.19 (1.05–1.35) | 74.3 | 70.7 | −3.6 |
| + with surgery | 2,524 (30.0) | 1.00 (ref) | 0.78 (0.68–0.88) | 0.99 (0.87–1.13) | 1.15 (1.01–1.31) | 1.20 (1.06–1.37) | 75.3 | 71.5 | −3.8 |
| Stage II&III | 8,957 (47.1) | 1.00 (ref) | 0.90 (0.84–0.96) | 1.02 (0.96–1.10) | 1.09 (1.02–1.17) | 1.15 (1.07–1.23) | 60.6 | 56.7 | −3.9 |
| + surgery | 8,321 (42.9) | 1.00 (ref) | 0.90 (0.84–0.97) | 1.02 (0.95–1.10) | 1.09 (1.01–1.17) | 1.15 (1.07–1.23) | 61.9 | 58.1 | −3.8 |
| + chemotherapy | 3,640 (38.4) | 1.00 (ref) | 0.91 (0.82–1.02) | 1.07 (0.96–1.19) | 1.13 (1.02–1.26) | 1.17 (1.05–1.30) | 65.8 | 61.5 | −4.3 |
| Stage III colon cancer | 2,726 (47.4) | 1.00 (ref) | 0.94 (0.83–1.07) | 1.14 (1.01–1.29) | 1.17 (1.03–1.34) | 1.13 (0.99–1.28) | 59.2 | 55.7 | −3.5 |
| + with R0 surgery | 2,280 (47.7) | 1.00 (ref) | 0.95 (0.83–1.08) | 1.13 (0.99–1.30) | 1.14 (0.99–1.31) | 1.10 (0.96–1.26) | 61.6 | 59.0 | −2.6 |
| + with chemotherapy | 1,142 (36.3) | 1.00 (ref) | 0.88 (0.73–1.06) | 1.19 (0.99–1.43) | 1.11 (0.92–1.35) | 1.18 (0.98–1.43) | 68.6 | 64.2 | −4.4 |
| Stage II & III rectal cancer | 3,102 (45.3) | 1.00 (ref) | 0.93 (0.83–1.04) | 1.04 (0.93–1.17) | 1.12 (1.00–1.26) | 1.18 (1.05–1.32) | 55.7 | 50.8 | −4.9 |
| + radiotherapy | 1,738 (40.1) | 1.00 (ref) | 0.87 (0.75–1.02) | 1.06 (0.91–1.24) | 1.16 (1.00–1.34) | 1.15 (1.00–1.34) | 60.1 | 56.4 | −3.7 |
| + neoadjuvant radiotherapy | 751 (30.2) | 1.00 (ref) | 0.82 (0.66–1.02) | 0.98 (0.79–1.22) | 0.95 (0.76–1.19) | 1.13 (0.91–1.41) | 60.9 | 56.1 | −4.8 |
Ref, reference; Q, quintile; Significant hazard ratios (p < 0.05) are printed in bold.
a
adjusted for age, sex, period, cancer site (for overall analyses), cancer grade and cancer stage (for stage II&III analyses).
b
five-year overall survival derived from the direct adjusted survival curves from the adjusted Cox proportional hazard regression model.