TABLE 2.
Hemoglobin analysis of cord blood.
| Phenotype | Number | Hb Type | Hb (g/dL) | MCV (fL) | MCH (pg) | Hb A % |
Hb F % |
Hb E % |
Hb Bart’s % |
||||
| HPLC | CE | HPLC | CE | HPLC | CE | HPLC | CE | ||||||
| Normal | 339 | FA | 15.5 ± 1.3 | 110.0 ± 4.8 | 35.9 ± 1.4 | 18.3 ± 6.8 | 81.6 ± 6.9 | 0.7 ± 0.4 | 0.0 ± 0.1 | ||||
| Hb E heterozygote | 86 | EFA | 15.4 ± 1.4 | 108.6 ± 5.0 | 35.4 ± 1.6 | 10.0 ± 3.8 | 86.1 ± 4.8 | 3.8 ± 1.3 | 0.7 ± 0.4 | 0.0 ± 0.1 | |||
| Hb E heterozygote with α-thalassemia 1 heterozygote t | 6 | EFA Bart’s | 14.4 ± 0.4 | 87.9 ± 3.6 | 28.0 ± 1.4 | 7.6 ± 4.0 | 83.1 ± 2.7 | 4.4 ± 4.3 | 8.6 ± 1.7 | 4.8 ± 1.0 | |||
| Hb E homozygote | 9 | EF | 14.5 ± 2.1 | 103.0 ± 6.7 | 34.0 ± 2.5 | ND | 81.4 ± 4.5 | ND | 8.0 ± 3.5 | ND | ND | ||
| β-thalassemia/Hb E disease | 4 | EF | 14.8 ± 2.3 | 105.7 ± 6.3 | 34.1 ± 2.1 | 0 | 93.0 | 90.2 ± 4.5 | 2.0 | 9.2 ± 4.0 | 1.0 | 0 ± 0 | |
| α-thalassemia 1 heterozygote | 17 | FA Bart’s | 13.4 ± 1.0 | 89.8 ± 3.4 | 28.0 ± 1.2 | 23.6 ± 5.3 | 71.5 ± 5.4 | 9.2 ± 1.1 | 4.6 ± 0.5 | ||||
| Hb H disease | 2 | FA Bart’s | 74 | 22 | 30 | 43.5 | ND | 52.0 | ND | 0 | ND | 24.2 | ND |
| Hb H-CS disease | 3 | CSFA Bart’s | 12.0 ± 0.1 | 97.2 ± 1.7 | 26.4 ± 0.5 | ND | 20.0 ± 8.2 | ND | 46.3 ± 7.0 | 0 | ND | 32.1 ± 3.1 | |
| Hb CS homozygote | 1 | CSFA Bart’s | 12.3 | 115.0 | 30.0 | 13.9 | ND | 78.5 | ND | 0 | ND | 15.0 | ND |
ND, not determined.