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. 2020 Jun 4;11:1166. doi: 10.3389/fmicb.2020.01166

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Copyright © 2020 Greppi, Asare, Schwab, Zemp, Stephan and Lacroix.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phylogenetic tree based on core genes of 65 L. reuteri strains from different hosts (25 genomes from this study and 40 from NCBI, Supplementary Table S1) based on the neighbor-joining method (PHYLIP implementation). Different colors represent different hosts, blue: human; yellow: chicken; pink: pig; brown: mouse/rat; light blue: cow; red: goat; green: horse; brown/green: sheep; black: sourdough. The red branches indicate the reuterin-negative strains. A, B and C indicate identified clusters in the gene content tree (Figure 1). Strains which harbor AMR genes for tetracycline (tet) and erythromycin (ery) are indicated as tetR and eryR, respectively.