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. 2020 Jun 4;11:1166. doi: 10.3389/fmicb.2020.01166

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Copyright © 2020 Greppi, Asare, Schwab, Zemp, Stephan and Lacroix.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagrams showing number of reciprocal best hits among different L. reuteri subset of core genomes. (A) Number of shared and unique genes of core genomes of cluster A (poultry/human lineage VI), cluster B (lineages human II, herbivore VII, porcine IV and rodent III) and cluster C (lineages rodent I, rodent III, herbivore VIII and porcine V). (B) Number of shared and unique genes of poultry VI genomes and human VI genomes. (C) Number of shared and unique genes between human VI and human II strains. (D) Number of shared and unique between poultry VI, human VI and human II lineages. Unique genes of human/poultry VI clades (A) and human VI isolates (B) are listed in Supplementary Table S3.