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. 2020 Jun 30;15(6):e0234712. doi: 10.1371/journal.pone.0234712

Table 1. Distribution of dogs with chronic kidney disease according to laboratory and nutrition parameters and their influence on survival.

Item N. dogs (%) Survival median (days) p
Stage1 2 50 (43.1) 475a <0.0001
3 43 (37.1) 187b
4 23 (19.8) 13c
BCS2 1 to 3 48 (41.4) 125a 0.0391
4 and 5 35 (30.2) 103a
6 to 9 33 (28.4) 327b
MMS3 0 9 (7.8) 45a 0.0002
1 34 (29.2) 122a
2 51 (44.0) 206b
3 22 (19.0) 255c
Serum phosphorus4 ≤ 5.5mg/dL 31 (48.4) 573 0.0005
> 5.5mg/dL 33 (51.6) 136
Hematocrit4 ≤ 37% 59 (53.6) 99 0.0001
> 37% 51 (46.4) 415
Serum albumin4 ≤ 2.3g/dL 18 (17.5) 128 0.2260
> 2.3g/dL 85 (82.5) 263
Appetite Anorexia 38 (32.8) 33a 0.0007
Hyporexia 38 (32.8) 246b
No alteration 40 (34.4) 429b
Feeding method Feeding tube 41 (35.4) 32 <0.0001
Voluntary 75 (64.6) 309
Type of food5 Renal6 63 (54.3) 309 0.0009
Other 53 (45.7) 92

1Staging according to IRIS [10]

2Body condition score according to Laflamme [20]

3Muscle mass score according to Michel et al. [21]

4Data not present for all dogs in the study

5Type of food consumed for 75% of the survival time or more

6Commercial or homemade diet formulated by the veterinarians of the Nutrology Service team of the hospital (16% crude protein and 0.3% phosphorus in dry matter basis)

a,b,cMedians with more than two variables with different letters were statistically different (p≤0.05).