Figure 3. LINC01268 acting as a sponge of miR-217. A, The potential targeted miRNA for LINC01268 was identified by the miRDB website. B, The expression of miR-217 in bone marrow tissues from acute myeloid leukemia (AML) patients and healthy donors (control) was evaluated by qRT-PCR. C, The correlation between LINC01268 and miR-217 was evaluated by the Pearson correlation analysis. D, The expression of miR-217 in AML cells transfected with miR-217 mimic was detected by qRT-PCR. E, The luciferase activity of the reporter with LINC01268 wild type (WT) or mutated (MUT) was evaluated by the luciferase reporter assay. F, RIP assay demonstrated that miR-217 and LINC01268 were greatly enriched in the Ago2 antibody group. G, The binding relationship between miR-217 and LINC01268 was further confirmed by RIP assay. Data are reported as means±SD. **P<0.01 vs the control group (ANOVA and t-test). NC: control.