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ROC curve of potential discriminant metabolites for ROP. C3DC is the best among all identified discriminant metabolites at predicting ROP, the diagnostic threshold of which is around 0.04 µmol/L, with high sensitivity (97.5%) and specificity (68.3%); followed by glycine (sensitivity = 92.5% and specificity = 58.5%), which is notably inferior at predicting than C3DC.
