Table 3. Summary of the potential diagnostic escape variants assessed.
| Variant | Diagnostic assay | Documented association with diagnostic failure | Prevalence in dataset | ||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 16S rRNA C1209A (four alleles) | Aptima GC Combo | Yes (Guglielmino et al., 2019) | 0.11% | 0.09% | 0% | 0% | 0% |
| N. meningitidis-like porA | In-house (Whiley et al., 2004; Whiley et al., 2005) | Yes (Whiley et al., 2011; Golparian et al., 2012) | 0.11% | 0.05% | 0% | 0% | 0% |
| cppB deletion | In-house (Diemert et al., 2002; Van Dyck et al., 2001) | Yes (Bruisten et al., 2004) | 1.12% | 0.05% | 0.47% | 0% | 7.29% |
| DR-9A G168A | Roche COBAS 4800 CT/NG | No | 0% | 0.09% | 0% | 0% | 0% |