FIGURE 2.

Meta-analysis of the associations between dietary linoleic acid intake and mortality from all causes (A), CVD (B), and cancer (C) in prospective cohort studies. For each study, RR corresponds to the comparison of extreme quantiles of dietary linoleic acid intake; the area of the grey square is proportional to the weight of the study, which is the inverse of the variance of the log RR; dots and horizontal lines represent RRs and 95% CIs. Diamonds depict pooled estimates from random-effects inverse-variance–weighted meta-analyses. AARP-DHS, NIH–American Association of Retired Persons Diet and Health Study; ARIC-Men, male participants from the Atherosclerosis Risk in Communities Study; ATBC, Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study; Canada-BC, Canada Breast Cancer Study, CHNS, China Health and Nutrition Survey; CSPOC-BC, Cancer Surveillance Program of Orange County–Breast Cancer; CVD, cardiovascular disease; FMC, Finnish Mobile Clinic Health Study; HPFS, Health Professionals Follow-Up Study; IIHD, Ischemic Heart Disease Study; InCHIANTI, the InCHIANTI (Invecchiare in Chianti, aging in the Chianti area) study; Italian elderly, a cohort of old people recruited in Italy; IWHS, Iowa Women's Health Study; KIHD, Kuopio Ischemic Heart Disease Risk Factor Study; LIBCSP, Long Island Breast Cancer Study Project; MDC, Malmo Diet and Cancer Cohort Study; MRFIT, Multiple Risk Factor Intervention Trial; NBSS, National Breast Screening Study; NHS, Nurses’ Health Study; Örebro-PC, Örebro Prostate Cancer Study; VIP-Men, male participants from the Västerbotten Intervention Program.