Table 1.
Details of 18 DNA repair genes
| Official symbol | Official full name | Locus |
|---|---|---|
| BLM | BLM RecQ like helicase | 15q26.1 |
| CDK12 | Cyclin‐dependent kinase 12 | 17q12 |
| ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 19q13.32 |
| EXO1 | Exonuclease 1 | 1q43 |
| FANCA | FA complementation group A | 16q24.3 |
| FANCM | FA complementation group M | 14q21.2 |
| KNTC1 | Kinetochore associated 1 | 12q24.31 |
| MDC1 | Mediator of DNA damage checkpoint 1 | 6p21.33 |
| MLH3 | mutL homolog 3 | 14q24.3 |
| MSH2 | mutS homolog 2 | 2p21‐p16.3 |
| MSH3 | mutS homolog 3 | 5q14.1 |
| PALB2 | Partner and localizer of BRCA2 | 16p12.2 |
| POLD1 | DNA polymerase delta 1, catalytic subunit | 19q13.33 |
| POLE | DNA polymerase epsilon, catalytic subunit | 12q24.33 |
| PRKDC | Protein kinase, DNA‐activated, catalytic subunit | 8q11.21 |
| RAD50 | RAD50 double‐strand break repair protein | 5q31.1 |
| SHPRH | SNF2 histone linker PHD RING helicase | 6q24.3 |
| TOPBP1 | DNA topoisomerase II binding protein 1 | 3q22.1 |