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. Author manuscript; available in PMC: 2020 Jun 30.
Published in final edited form as: J Proteome Res. 2019 Jun 10;18(7):2759–2770. doi: 10.1021/acs.jproteome.9b00026

Figure 5.

Figure 5.

Neuropeptide changes identified by ESI-MS at different time points in a single tissue (a) indicating the stress-related function of the peptide and in multiple tissues (b), indicating the hormonal role of the peptide when pH declined. X-axis, exact mass of neuropeptides (M+H+); Y-axis, peak intensity ratio of stress over control; Error bar, standard deviation; Red dash line indicated no change in peptide levels. Student’s t-test was applied to evaluate the significance of neuropeptide level changes upon stress compared to control groups. *p<0.05; **p<0.005; ***p<0.001. Brn, brain.