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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Adv Exp Med Biol. 2019;1193:35–52. doi: 10.1007/978-981-13-6260-6_2

Fig. 1.

Fig. 1

Exogenous sources of reactive aldehyde exposure. These include air pollution produced by industrial power plants and automobiles, alcoholic beverages, tobacco products including cigarettes and e-cigarettes, fried foods, cosmetics, and lacquers in paints. As pictured, the ALDH2 enzyme reduces an aldehyde to a less harmful acid. However, for those with an ALDH2*2 variant, the efficiency of this metabolism is reduced by >60%