Table 1.
Demographic Data
| Characteristics | Healthy (N=20) | Sepsis (N=20) | p-value |
|---|---|---|---|
| Gender, n (%) | |||
| Male | 11 (55) | 11 (55) | 1.0 |
| Female | 9 (45) | 9 (45) | 1.0 |
| Mean age, years ± SD | 61 ± 14.1 | 60 ± 12.2 | 1.0 |
| Time of diagnosis: days after | |||
| hospitalization; Median (IQ range) | N/A | 11 (6–28) | N/A |
| WBC count (x103cells/µL ± SD) | 6.7 ± 2.3 | 16.5 ± 9.6 | <0.001 |
| Absolute neutrophil | 4.1 ± 2.0 | 14.3 ± 9.4 | <0.001 |
| Underlying illnesses, n (%) | |||
| Diabetes mellitus | 6 (30) | 5 (25) | >0.99 |
| Hypertension | 6 (30) | 7 (35) | >0.99 |
| Ischemic heart disease | 0 (0) | 2 (10) | 0.49 |
| Dyslipidemia | 3 (15) | 1 (5) | 0.61 |
| Malignancy | 0 (0) | 8 (40) | 0.003 |
| Organisms (identified in blood) | |||
| Staphylococcus spp. | N/A | 1 (5) | N/A |
| Escherichia spp. | N/A | 2 (10) | N/A |
| Candida spp. | N/A | 2 (10) | N/A |
| Unidentified organisms | N/A | 15 (75) | N/A |
| Plasma level of ascorbate or vitamin C (mg/L ± SD) | 7.79 ± 3.86 | 1.03 ± 2.07 | <0.01 |
Abbreviations: SD, standard deviation; WBC, white blood cell; N/A, not applicable.