Fig. 4.

Effects of BCAA aminotransferase overexpressions on bacitracin production. A: Effects of ilvE, ywaA and ybgE overexperessions on bacitracin yields, B: Effects of replacing the promoter of ybgE by PbacA on bacitracin production, C: The concentrations of intracellular BCAAs, D: The concentrations of extracellular BCAAs. Each experiment was repeated at least three times, and data are represented as the means of three replicates and bars represent the standard deviations, ∗, P ​< ​0.05; and ∗∗, P ​< ​0.01 indicate the significance levels between recombinant strains and control strain.