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. 2020 Jun 24;11:1290. doi: 10.3389/fimmu.2020.01290

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Copyright © 2020 Thorenoor, Kawasawa, Gandhi and Floros.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression in AMs of SP-A1 (6A², 6A⁴) and SP-A2 (1A³) variants as well as KO male and female after K. pneumoniae infection at the 6 h time point. A total of 196 genes (SP-A1 (6A²), (A), 494 genes (SP-A1 (6A⁴), (B), 397 genes (SP-A2 (1A³), (C) and 858 genes (KO, D) were identified with a P-value < 0.05 (n = 4/group). Significant sex differences in the expression of genes were observed for all variants studied and the KO. The significant differences (P < 0.01 and P < 0.001) between sexes are noted with an asterisk (** and ***).