Table 4.
Formulations and dosages of common vaccines to protect against pertussis, and tetanus disease for use in pregnant women in selected countries in Europe, North America, South America, and Asia.
| Vaccine formulation | Antigen composition | References | Selected countries # |
|---|---|---|---|
| Against tetanus | |||
| Td (MassBiologics) | Diphtheria toxoid: 2 Lf Tetanus toxoid: 2 Lf |
(70) | South America: Honduras Asia: Thailand, Philippines, Malaysia Africa: Egypt, Gambia, Senegal, Gabon, Cameron, Botswana |
| TT adsorbed (Serum Institute of India) | TT ≥ 5 Lf | (71) | |
| Against pertussis | |||
| Tdap (Adacel, Sanofi Pasteur) | Diphtheria toxoid: 2 Lf Tetanus toxoid: 5 Lf PT: 2.5 μg FHA: 5 μg PRN: 3 μg FIM: 5 μg |
(70) | Europe: Belgium, Spain, United Kingdom, Italy North America: Canada, United States of America South America: Argentina, Brazil, Columbia, Chile, Mexico, Uruguay Asia: Singapore Africa: Australia and New Zealand |
| Tdap (Boostrix, GlaxoSmithKline) | Diphtheria toxoid: 2.5 Lf Tetanus toxoid: 5 Lf PT: 8 μg FHA: 8 μg PRN: 2.5 μg |
||
| Against influenza* | |||
| Quadrivalent inactivated influenza vaccin | Europe: Albania, Belgium, Hungary, Romania, Russian Federation, Spain, Sweden, United Kingdom, Italy North America: Canada, United States of America South America: Argentina, Brazil, Columbia, Ecuador, Bolivia, Mexico, Uruguay Australia and New Zealand Asia: Singapore, Thailand Africa: South Africa, Algeria |
||
| Afluria Quadrivalent (Seqirus) FluLaval Quadrivalent (GlaxoSmithKline) Flucelvax Quadrivalent (Seqirus) Fluzone Quadrivalent (Sanofi Pasteur) |
Influenza A/Brisbane/02/2018 (H1N1)pdm09-like virus Influenza A/Kansas/14/2017 (H3N2)-like virus Influenza B/Colorado/06/2017-like (Victoria lineage) virus Influenza B/Phuket/3073/2013–like virus (Yamagata lineage) Dosage: Hemagglutinin 15 μG/dose (each virus) |
(72) | |
| Trivalent inactivated influenza vaccine | |||
| Fluad (Seqirus) | Influenza A/Brisbane/02/2018 (H1N1)pdm09-like virus Influenza A/Kansas/14/2017 (H3N2)-like virus Influenza B/Colorado/06/2017-like (Victoria lineage) virus Dosage: Hemagglutinin 15 μG/dose (each virus) |
(72) | |
TT, Tetanus toxoid; Td, Tetanus diphtheria; Tdap, tetanus-diphtheria-acellular-pertussis; Lf, limit of flocculation; PT, pertussis toxin; FHA, filamentous hemagglutinin; PRN, pertactin; FIM, fimbria 2/3.
*
Influenza vaccines compositions are reviewed each year and updated as needed. Composition presented is for 2019-20 influenza season.
#
Source: World Health Organization website: https://apps.who.int/immunization_monitoring/globalsummary.