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. 2020 Jun 19;8:681. doi: 10.3389/fbioe.2020.00681

TABLE 1.

Semiquantitative analysis of expression of several epithelial markers as determined by immunofluorescence.

In vitro 1 week In vitro 2 weeks In vitro 3 weeks In vivo 3 months In vivo 12 months Control human cornea Control rabbit cornea
CK3/12 HOC + + ++ +++ +++ +++ +++
HHC ++ +++ +++
PKG HOC + + +++ +++ +++ +++ ±
HHC ++ ++ +++ +++
CRY-αA HOC + ++ +++ +++ +++ +++ +++
HHC + + +++ +++ +++
CRY-αB HOC ± + ± ++ +++ +++
HHC ± + + + +++
CRY-β HOC + + ++ ++ ++ ++ ++
HHC + + ++ +
CRY-λ1 HOC ++ ++ ++ + + +++ ±
HHC ++ ++ ++ + ++
CRY-Z HOC + ++ ++ ++ +++ +
HHC + ++ +++ ++ +++

HOC, human orthotypical cornea; HHC, human heterotypical cornea.