TABLE 5.
Prevalence of OI by Sex in CD and UC
| 5a. Crohn’s Disease | |||||
|---|---|---|---|---|---|
| Males, No. | Females, No. | Prevalence, Malesa | Prevalence, Femalesa | PR in Males vs Females | |
| Histoplasmosis | 70 | 100 | 115.1 | 108.2 | 1.06; 95% CI, 0.78–1.44; P = 0.746 |
| Cryptococcus | 20 | 20 | 32.9 | 21.6 | 1.52; 95% CI, 0.82–2.82; P = 0.242 |
| Pneumocystis | 40 | 20 | 43.3 | 32.9 | 3.04; 95% CI, 1.78–5.20; P < 0.0001 |
| Aspergillosis | 60 | 50 | 64.9 | 82.2 | 1.82; 95% CI, 1.25–2.65; P = 0.002 |
| Candidiasis | 2110 | 6870 | 3469.3 | 7431.8 | 0.47; 95% CI, 0.45–0.49; P < 0.0001 |
| Legionellosis | 20 | 10 | 32.9 | 10.8 | 3.04; 95% CI, 1.42–6.49; P = 0.005 |
| Pneumococcal disease | 180 | 270 | 296.0 | 292.1 | 1.01; 95% CI, 0.84–1.22; P = 0.927 |
| C. difficile | 1500 | 2480 | 2466.3 | 2682.8 | 0.92; 95% CI, 0.86–0.98; P = 0.009 |
| Influenza | 1240 | 2310 | 2038.8 | 2498.9 | 0.81; 95% CI, 0.76–0.87; P < 0.0001 |
| HPV | 1560 | 4420 | 2564.9 | 4781.5 | 0.54; 95% CI, 0.41–0.57; P < 0.0001 |
| EBV | 140 | 230 | 230.2 | 248.8 | 0.93; 95% CI, 0.75–1.14; P = 0.502 |
| CMV | 160 | 190 | 263.1 | 205.5 | 1.28; 95% CI, 1.04–1.58; P = 0.025 |
| HSV | 720 | 2260 | 1183.8 | 2444.8 | 0.48; 95% CI, 0.45–0.53; P < 0.0001 |
| Tuberculosis | 110 | 130 | 209.0 | 171.3 | 1.29; 95% CI, 1.00–1.66; P = 0.061 |
| 5b. Ulcerative Colitis | |||||
| Males, No. | Females, No. | Prevalence, Malesa | Prevalence, Femalesa | PR in Males vs Females | |
| Histoplasmosis | 40 | 70 | 76.0 | 92.3 | 0.82; 95% CI, 0.56–1.22; P = 0.378 |
| Cryptococcus | 10 | 10 | 19.0 | 13.2 | 1.44; 95% CI, 0.60–3.46; P = 0.547 |
| Pneumocystis | 30 | 30 | 39.5 | 57.0 | 1.44; 95% CI, 0.87–2.39; P = 0.197 |
| Aspergillosis | 50 | 60 | 95.0 | 79.1 | 1.20; 95% CI, 0.83–1.75; P = 0.388 |
| Candidiasis | 1760 | 5560 | 3343.5 | 7327.4 | 0.46; 95% CI, 0.43–0.48; P < 0.0001 |
| Legionellosis | 20 | 20 | 38.0 | 26.4 | 1.44; 95% CI, 0.78–2.68; P = 0.316 |
| Pneumococcal disease | 160 | 230 | 304.0 | 303.1 | 1.00; 95% CI, 0.82–1.23; P > 0.999 |
| C. difficile | 2000 | 3020 | 3799.4 | 3980.0 | 0.95; 95% CI, 0.90–1.01; P = 0.100 |
| Influenza | 1110 | 1890 | 2108.7 | 2490.8 | 0.85; 95% CI, 0.79–0.91; P < 0.0001 |
| HPV | 1300 | 3960 | 2469.6 | 5218.8 | 0.47; 95% CI, 0.44–0.50; P < 0.0001 |
| EBV | 120 | 170 | 228.0 | 224.0 | 1.02; 95% CI, 0.81–1.29; P = 0.929 |
| CMV | 220 | 200 | 417.9 | 263.6 | 1.59; 95% CI, 1.31–1.92; P < 0.0001 |
| HSV | 600 | 1870 | 1139.8 | 2464.4 | 0.46; 95% CI, 0.42–0.51; P < 0.0001 |
| Tuberculosis | 70 | 90 | 133.0 | 118.6 | 1.12; 95% CI, 0.82–1.53; P = 0.522 |
aPrevalence reported per 100,000.