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YbeY is required for the virulence of P. aeruginosa in the acute pneumonia model. (A) Mice were infected intranasally with the indicated strains. At 12 h postinfection, lungs from the infected mice were isolated. The bacterial loads were determined by serial dilution and plating. ***, P < 0.001 by Student’s t test. (B) RNA-seq results. Values reported as log(RPKM) of the genes with more than 2-fold difference in expression between the ΔybeY mutant and the wild-type PA14.
