FIG 8.

Direct BBC treatment inhibits the infectivity of SFV and CHIKV virions. Stocks of ppSFV, CHIKV, and ppVSV were treated with the indicated DMSO or BBC concentrations for 1 h at 37°C. Infectious virus titer was quantitated by 50% tissue culture infective dose (TCID₅₀) assay, and viral titer reduction was calculated based on the log difference between control and treated samples. The graphs represent the means with individual data points plotted for two to three independent experiments. Multiple t tests were performed to assess the statistical significance of viral titer reduction between viruses under each treatment condition. ***, P < 0.001; **, P < 0.01.