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(A) The predicted binding sites between miR-19b and SOCS6 are illustrated. (B) The targeting relationship between miR-19b and SOCS6 was identified by luciferase reporter assay. (C) HRMECs were divided into five groups and transfected with miR-19b mimics, miR-19b inhibitor or NCs. The mRNA expression of SOCS6 was detected by qRT-PCR. (D) Protein levels of SOCS6 were measured by Western blotting; n=3, *P<0.05, **P<0.01.
