Fig. 2.
The key pocket proposed to exist in the Cro-EM spike protein structure from Covid-19 from the results of the DoGSiteScorer server. The site is adjacent to where major movements occur when the virus changes conformation on encountering the host cell receptor, preparing it for infection. a. Depicts the residues lining the pocket, name and sequence number, along the “axis” of the pocket. b. 90O rotation about the viewed vertical axis from the view in A perpendicular to the “axis” of the pocket. This view is the one used to show the chosen poses in Fig. 5