TABLE 1.
Demographic characteristics of participants
| Characteristic | CS | MCI‐DS | DS‐AD |
|---|---|---|---|
| N | 225 | 44 | 36 |
| Age | 42.4 ± 9.1 | 52.9 ± 6.9 * | 54.3 ± 6.2 * |
| Sex N (%) | |||
| Male | 127 (52.5) | 35 (68.6) | 21(48.8) |
| Female | 115 (47.5) | 16 (31.4) * | 22 (51.2) |
| Level of function N (%) | |||
| Mild/moderate | 228 (94.2) | 37 (88.1) | 37 (88.1) |
| Severe/profound | 9 (3.7) | 5 (11.9) | 5 (11.6) |
| Ethnicity N (%) | |||
| White | 234 (97.1) | 47 (92.2) * | 40 (93.0) |
| Non‐white | 7 (2.9) | 4 (7.8) | 3 (7.0) |
| APOE ɛ4 allele N (%) | 45 (21.1) | 15 (34.1) | 14 (35.0) |
Note: Significance P‐value <.05*, <.001**
Abbreviations: AD, Alzheimer's disease; APOE, apolipoprotein E; CS, cognitively stable; DS, Down syndrome; MCI, mild cognitive impairment