Skip to main content
. 2019 Feb 11;13(7):884–893. doi: 10.1093/ecco-jcc/jjz014

Figure 2.

Figure 2.

Genome-wide transcriptomic analysis distinguishes UC from sporadic colon cancer. Principle component analyses using RNA sequencing data comparing: A] UC colon cancer, non-dysplastic tissue adjacent to a UC cancer, sporadic colon cancer, and normal tissue adjacent to a sporadic colon cancer; B] UC-associated colon cancer and adjacent non-dysplastic UC tissue; and C] sporadic colon cancer and adjacent normal tissue. D] Significantly enriched GAGE pathways in IBD cancers compared with sporadic colon cancers. E] Venn diagram demonstrating the number of significantly differentially expressed genes in UC-associated colon cancers compared with adjacent tissues with active inflammation and UC-associated colon cancers compared with no inflammation [quiescent] in the adjacent tissue. UC, ulcerative colitis; IBD, inflammatory bowel disease.