Table 1.
Clinical characteristics of subjects with colon cancer included in the analysis.
| DNA methylation analysis | RNAseq analysis | |||
|---|---|---|---|---|
| IBD-CRC [n = 11] | Sporadic CRC [n = 11] | IBD-CRC [n = 9] | Sporadic CRC [n = 8] | |
| Age [mean] | 47.2 | 65.5 | 49.2 | 57.25 |
| Sex [male %] | 100% | 45% | 100% | 25% |
| Location | ||||
| Left colon | 7 | 7 | 6 | 5 |
| Right colon | 4 | 4 | 3 | 3 |
| Race | ||||
| Caucasian | 8 | 5 | 7 | 5 |
| AA | 0 | 3 | 0 | 2 |
| Unknown | 3 | 3 | 2 | 1 |
| Ethnicity | ||||
| Hispanic | 2 | 0 | 1 | 0 |
| Tumour grade | ||||
| Low | 4 | 6 | 4 | 6 |
| High | 4 | 5 | 5 | 2 |
| Mucinous | 4 | 1 | 4 | 0 |
| Signet ring | 0 | 1 | 0 | 0 |
| Tumour multiplicity | ||||
| Adenocarcinoma | 3 | 0 | 3 | 0 |
| Dysplasia | 5 | N/A | 4 | N/A |
| PSC | 1 | 0 | 1 | 0 |
| Inflammation | ||||
| Quiescent | 4 | N/A | 4 | |
| Mild | 1 | 1 | ||
| Moderate | 4 | 3 | ||
| Severe | 2 | 1 | ||
| Pancolitis | 100% | N/A | 100% | N/A |
IBD, inflammatory bowel disease; CRC, colorectal cancer; AA, African American; PSC, primary sclerosing cholangitis; N/A, not available.