Table 3. The transcription factor targets of differentially expressed glutathione peroxidases in AML (LinkedOmics).
| GPXs | Gene set | Leading edge number | P value |
|---|---|---|---|
| GPX-1 | V$AP1_Q4_01 | 58 | 0.00E+00 |
| V$AP1_Q6 | 59 | 0.00E+00 | |
| V$AP1_Q6_01 | 50 | 0.00E+00 | |
| V$LFA1_Q6 | 58 | 0.00E+00 | |
| V$SRF_01 | 19 | 0.00E+00 | |
| GPX-2 | V$FOX_Q2 | 50 | 0.00E+00 |
| V$USF_C | 48 | 0.00E+00 | |
| V$ELK1_02 | 65 | 0.00E+00 | |
| V$NRF2_01 | 60 | 0.00E+00 | |
| V$YY1_01 | 53 | 0.00E+00 | |
| GPX-4 | V$SRF_01 | 15 | 3.51E−03 |
| V$SP1_Q6_01 | 66 | 0.00E+00 | |
| V$AP1_Q4_01 | 57 | 0.00E+00 | |
| V$LFA1_Q6 | 68 | 0.00E+00 | |
| V$SOX5_01 | 61 | 0.00E+00 | |
| GPX-7 | V$E2F1DP1_01 | 69 | 0.00E+00 |
| V$E2F1_Q4_01 | 65 | 0.00E+00 | |
| V$E2F1_Q6 | 70 | 0.00E+00 | |
| V$E2F1DP1RB_01 | 70 | 0.00E+00 | |
| V$E2F1DP2_01 | 69 | 0.00E+00 | |
| GPX-8 | V$NFY_Q6 | 41 | 0.00E+00 |
| V$IRF1_01 | 43 | 0.00E+00 | |
| V$HNF1_01 | 36 | 0.00E+00 | |
| V$AP3_Q6 | 56 | 0.00E+00 | |
| V$SMAD3_Q6 | 71 | 0.00E+00 |
AML, acute myeloid leukemia; GPX, glutathione peroxidase; LeadingEdgeNum, the number of leading edge genes; V$, the annotation found in Molecular Signatures Database (MSigDB) for transcription factor (TF).