Figure 3. Differential phosphorylation site preference of PP2A‐B56 and PP2A‐B55.

• A
  Michaelis–Menten kinetic parameters of purified PP2A‐B56α and PP2A‐B55α holoenzymes were determined against the indicated phosphopeptides. Mean and standard deviation shown in plots as black bars (n = 3 independent experiments).
• B–D
  In vitro dephosphorylation by the PP2A‐B55α and PP2A‐B56α holoenzymes of panels of phosphorylated peptides as indicated. Mean and standard deviation shown in plots as black bars (n = 3 independent experiments).