Forest plot showing effect sizes for mean-scaled variability of immune parameters in depression compared with healthy controls. The coefficient of variation ratio (CVR) was significant decreased for IL-12, IL-13, IL-2R, CRP, and IFNγ, indicating lower variability of these immune parameters in patients compared with controls, and significantly increased for IL-2 and TGF β, indicating increased variability of these immune parameters in patients compared with controls.