Figure 4.

Freedom from heart failure hospitalization over a median follow-up time of 8.75 years. *Adjusted for age, sex, history of diabetes, and history of coronary artery disease (myocardial infarction, percutaneous coronary intervention, or coronary artery bypass grafting), left ventricular ejection fraction, and left ventricular remodelling type. The Kaplan–Meier survival curves are shown for heart failure hospitalization with patients categorized by normal vs. abnormal myocardial flow reserve (MFR ≥ 1.8 vs. <1.8) and normal vs. abnormal global longitudinal strain (GLS ≤ −18% vs. >−18%). Hazard ratios and P-values are displayed from Cox proportional hazard models comparing those with both abnormal vs. both normal myocardial flow reserve and global longitudinal strain.