Table 1. Patient Characteristics in the Propensity Score–Matched Samplea.
| Variable | Patients with cirrhosis (n = 3350) | Patients without cirrhosis (n = 11 848) | ||||
|---|---|---|---|---|---|---|
| Treatment group, No. (%) (n = 1675) | Control group, No. (%) (n = 1675) | P valueb | Treatment group, No. (%) (n = 5924) | Control group, No. (%) (n = 5924) | P valueb | |
| Age, mean (SD), y | 62.1 (10.2) | 62.8 (8.8) | .03 | 59.4 (11.7) | 59.7 (10.4) | .08 |
| Age group, y | ||||||
| <65 | 963 (57.5) | 972 (58.0) | 3827 (64.6) | 3714 (62.7) | ||
| 65-70 | 381 (22.8) | 364 (21.7) | 1255 (21.2) | 1319 (22.3) | ||
| 71-75 | 184 (11.0) | 186 (11.1) | 529 (8.9) | 551 (9.3) | ||
| >75 | 147 (8.8) | 153 (9.1) | .91 | 313 (5.3) | 340 (5.7) | .18 |
| Sex | ||||||
| Women | 616 (36.8) | 611 (36.5) | 2463 (41.6) | 2470 (41.7) | ||
| Men | 1059 (63.2) | 1064 (63.5) | .86 | 3461 (58.4) | 3454 (58.3) | |
| Race/ethnicity | ||||||
| White | 1193 (71.2) | 1217 (72.7) | 3959 (66.8) | 3909 (66.0) | ||
| Black | 336 (20.1) | 311 (18.6) | 1583 (26.7) | 1634 (27.6) | ||
| Hispanic | 61 (3.6) | 61 (3.6) | 159 (2.7) | 164 (2.8) | ||
| Other | 85 (5.1) | 86 (5.1) | .75 | 223 (3.8) | 217 (3.7) | .73 |
| Cirrhosis type | ||||||
| Decompensated | 483 (28.8) | 518 (30.9) | NA | NA | ||
| Compensated | 1192 (71.2) | 1157 (69.1) | .41 | NA | NA | |
| Conditions | ||||||
| HIV/AIDS | 62 (3.7) | 58 (3.5) | .71 | 457 (7.7) | 466 (7.9) | .76 |
| Hepatocellular cancer | 111 (6.6) | 137 (8.2) | .09 | 31 (0.5) | 37 (0.6) | .47 |
| Anemia | 683 (40.8) | 696 (41.6) | .65 | 1515 (25.6) | 1624 (27.4) | .02 |
| Lung disease | 462 (27.6) | 499 (29.8) | .16 | 1386 (23.4) | 1511 (25.5) | .01 |
| Cancer | 217 (13.0) | 207 (12.4) | .60 | 645 (10.9) | 701 (11.8) | .11 |
| Cardiac disease | 1307 (78.0) | 1324 (79.0) | .47 | 4052 (68.4) | 4172 (70.4) | .02 |
| Dementia | 98 (5.8) | 87 (5.2) | .41 | 276 (4.7) | 272 (4.6) | .86 |
| Psychiatric conditions | 832 (49.7) | 858 (51.2) | .37 | 3048 (51.4) | 3124 (52.7) | .16 |
| Diabetes | 665 (39.7) | 689 (41.1) | .40 | 1736 (29.3) | 1817 (30.7) | .32 |
| Eye disease | 303 (18.1) | 304 (18.2) | .96 | 992 (16.8) | 1051 (17.7) | .15 |
| Kidney disorders | 545 (32.5) | 557 (33.2) | .66 | 1312 (22.3) | 1395 (23.6) | .07 |
| Drug and alcohol-related disorder | 889 (53.1) | 946 (56.5) | .05 | 2950 (49.8) | 2917 (49.2) | .54 |
| Bone disease | 684 (40.8) | 664 (39.6) | .48 | 2423 (40.9) | 2549 (43.0) | .02 |
| ESKD | 72 (4.3) | 69 (4.1) | .80 | 227 (3.8) | 242 (4.1) | .48 |
Abbreviations: ESKD, end-stage kidney disease; NA, not applicable.
a
Patient characteristics were measured at baseline (time of treatment).
b
P values were calculated with unpaired, 2-tailed t tests for binary and continuous variables and with χ2 tests for categorical variables.