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. 2020 Jun 20;2020:2819658. doi: 10.1155/2020/2819658

Figure 5.

Figure 5

Gypenoside regulates mRNA expression of mitochondrial energy-related genes in the aorta. Mitochondrial energy-related genes Atp12a, Cox5a, Ndufb6, and Sdhc were analyzed by qPCR. (a) Atp12a mRNA is increased in ApoE−/− mice and reduced by gypenoside and simvastatin treatment; (b) Cox5a mRNA is increased in ApoE−/− mice and reduced by gypenoside and simvastatin treatment; (c) Ndufb6 mRNA is increased in ApoE−/− mice and is only reduced by simvastatin treatment; (d) Sdhc mRNA is increased in ApoE−/− mice and reduced by gypenoside and simvastatin treatment. All results are expressed as the mean ± SD of four different experiments (n = 3). ∗∗P < 0.01 between each group.