Table 1.

Descriptive statistics of the 4 phases of aspirin research.

Phases, Time span		Number of publications		Number of authors		Average number of authors		Number of journals
1. Original use
	1951-1955	208		318		1.76		117
	1956-1960	299		498		1.88		159
	1951-1960	507		794		1.83		218
2. In-depth studies of pharmacological mechanisms and side effects
	1961-1965	748		1310		2.01		301
	1966-1970	1268		2167		2.12		418
	1971-1975	2766		4880		2.40		696
	1976-1980	3797		7419		2.71		895
	1981-1985	4395		10,011		3.16		1033
	1986-1990	4470		11,600		3.50		1101
	1961-1990	17,444		31,787		2.90		2153
3. Repurposing for cardiovascular diseases
	1991-1995	5164		14,044		3.69		1256
	1996-2000	6353		17,694		4.10		1314
	1991-2000	11,517		28,818		3.91		1798
4. Repurposing for other diseases
	2001-2005	8099		27,784		4.22		1719
	2006-2010	9366		35,313		4.94		1974
	2011-2015	10,436		44,603		5.78		2410
	2016-2018	6018		30,796		6.73		1881
	2001-2018	33,919		118,857		5.33		3865
Total			63,387		171,559		4.39		5443