Table 1.
Baseline characteristics of the study population.
| Non-DM by A/C tertiles | DM | ||||||
|---|---|---|---|---|---|---|---|
| <1.08 N = 60 |
1.08-1.22 N = 62 |
>1.22 N = 60 |
p for trend | N = 95 | p non−DM versus DM | ||
| Age | 57.6 ± 11.6 | 58.3 ± 12.3 | 57.3 ± 12.0 | 57.1 ± 10.6 | 0.438 | 57.1 ± 11.5 | 0.725 |
| BMI (kg/m2) | 25.8 ± 3.9 | 26.4 ± 5.3 | 25.5 ± 3.2 | 25.6 ± 2.7 | 0.467 | 26.8 ± 3.3 | 0.038 |
| Men | 150 (82.4) | 53 (88.3) | 49 (79.0) | 48 (80.0) | 0.232 | 77 (81.1) | 0.779 |
| Smoking | 125 (68.7) | 46 (76.7) | 42 (67.7) | 37 (61.7) | 0.077 | 67 (70.5) | 0.752 |
| Time from symptom onset (hour) | 6.1 (2.9, 13.8) | 7.3 (3.8, 14.7) | 7.9 (3.3, 16.9) | 3.7 (2.3, 8.0) | 0.005 | 5.3 (2.7, 11.5) | 0.576 |
| Hypertension | 101 (55.5) | 36 (60.0) | 31 (50.0) | 34 (56.7) | 0.714 | 61 (64.2) | 0.162 |
| Dyslipidemia | 166 (91.2) | 54 (90.0) | 55 (88.7) | 57 (95.0) | 0.335 | 85 (89.5) | 0.638 |
| Prior PCI | 12 (6.6) | 3 (5.0) | 5 (8.1) | 4 (6.7) | 0.714 | 9 (9.5) | 0.390 |
| ABG (mg/dl) | 132.6 (119.5, 146.3) | 116.4 (108.5, 124.3) | 133.5 (126.1, 142.0) | 154.6 (139.0, 177.2) | <0.001 | 211.5 (177.2, 271.3) | <0.001 |
| HbA1c (%) | 5.7 (5.5, 5.9) | 5.8 (5.6, 6.0) | 5.7 (5.5, 5.9) | 5.6 (5.4, 5.8) | <0.001 | 7.9 (7.0, 9.3) | <0.001 |
| A/C | 1.15 (1.03, 1.27) | 0.97 (0.92, 1.03) | 1.15 (1.10, 1.18) | 1.34 (1.27, 1.46) | <0.001 | 1.21 (1.03, 1.38) | 0.127 |
| cTnI | 3.9 ± 8.6 | 4.9 ± 10.4 | 4.1 ± 8.8 | 2.5 ± 6.2 | 0.009 | 3.4 ± 7.1 | 0.583 |
| CK-MB | 70.9 ± 104.1 | 79.1 ± 109.7 | 82.4 ± 107.2 | 51.0 ± 93.4 | 0.038 | 56.1 ± 86.2 | 0.200 |
| WBC (106/l) | 10.6 ± 3.2 | 10.2 ± 3.0 | 10.3 ± 3.4 | 11.3 ± 3.2 | 0.082 | 10.6 ± 3.0 | 0.995 |
| Hb (g/l) | 147.1 ± 16.7 | 147.3 ± 17.4 | 147.3 ± 16.8 | 146.5 ± 16.2 | 0.993 | 149.1 ± 15.9 | 0.331 |
| TC (mg/dl) | 168.2 ± 40.0 | 168.2 ± 40.8 | 172.5 ± 37.1 | 163.8 ± 42.1 | 0.858 | 176.4 ± 40.2 | 0.108 |
| TG (mg/dl) | 135.9 ± 93.0 | 134.5 ± 79.2 | 130.5 ± 80.3 | 142.7 ± 116.3 | 0.988 | 185.9 ± 127.6 | <0.001 |
| HDL-C (mg/dl) | 43.1 ± 14.5 | 42.6 ± 21.2 | 43.5 ± 9.8 | 43.1 ± 9.9 | 0.074 | 40.9 ± 8.8 | 0.189 |
| LDL-C (mg/dl) | 107.1 ± 33.1 | 106.9 ± 35.1 | 110.5 ± 31.7 | 103.8 ± 32.7 | 0.888 | 111.2 ± 33.3 | 0.327 |
| Lp(a) (mg/l) | 179.8(84.0, 394.0) | 144.1(66.5, 318.1) | 207.3(99.0, 458.0) | 194.0(102.8, 357.0) | 0.130 | 130.2 (54.5, 309.8) | 0.070 |
| eGFR (mL/min/1.73 m2) | 94.6 ± 33.3 | 102.1 ± 40.9 | 91.5 ± 29.3 | 90.2 ± 27.6 | 0.183 | 99.5 ± 27.1 | 0.211 |
| Hs-CRP (mg/l) | 5.3 (2.5, 10.9) | 5.6 (2.9, 11.1) | 5.9 (2.8, 10.4) | 4.6 (1.8, 11.0) | 0.337 | 6.4 (2.7, 10.3) | 0.748 |
| LVEF (%) | 54.7 ± 6.5 | 55.3 ± 5.6 | 55.6 ± 6.9 | 53.2 ± 6.9 | 0.092 | 55.7 ± 5.4 | 0.208 |
| Aspirin | 63 (34.6) | 25 (41.7) | 19 (30.6) | 19 (31.7) | 0.251 | 41 (43.2) | 0.163 |
| P2Y12 inhibitor | 42 (23.1) | 17 (28.3) | 15 (24.2) | 10 (16.7) | 0.130 | 28 (29.5) | 0.245 |
| Statin | 34 (18.7) | 11 (18.3) | 12 (19.4) | 11 (18.3) | 1.000 | 13 (13.7) | 0.293 |
| Culprit vessels | 0.240 | 0.245 | |||||
| LAD | 88 (48.4) | 28 (46.7) | 26 (41.9) | 34 (56.7) | 47 (49.5) | ||
| LCX | 23 (12.6) | 5 (8.3) | 13 (21.0) | 5 (8.3) | 6 (6.3) | ||
| RCA | 71 (39.0) | 27 (45.0) | 23 (37.1) | 21 (35.0) | 42 (44.2) | ||
| LM disease | 5 (2.7) | 3 (5.0) | 1 (1.6) | 1 (1.7) | 0.265 | 1 (1.1) | 0.358 |
| MVD | 127 (69.8) | 43 (71.7) | 41 (66.1) | 43 (71.7) | 1.000 | 77 (81.1) | 0.043 |
| Pre-TIMI flow | 0.763 | 0.480 | |||||
| 0 | 124 (68.1) | 39 (65.0) | 43 (69.4) | 42 (70.0) | 56 (58.9) | ||
| 1 | 9 (4.9) | 4 (6.7) | 3 (4.8) | 2 (3.3) | 5 (5.3) | ||
| 2 | 15 (8.2) | 6 (10.0) | 4 (4.8) | 5 (8.3) | 10 (10.5) | ||
| 3 | 34 (18.7) | 11 (18.3) | 12 (19.4) | 11 (18.3) | 24 (25.3) | ||
| Aspiration | 107 (58.8) | 35 (58.3) | 37 (59.7) | 35 (58.3) | 1.000 | 65 (68.4) | 0.117 |
| Predilation | 148 (81.3) | 48 (80.0) | 50 (80.6) | 50 (83.3) | 0.640 | 72 (75.8) | 0.280 |
Data shown are number (%), median (25th, 75th percentiles), or mean ± SD. ABG: acute blood glucose; A/C: acute-to-chronic glycemic ratio; BMI: body mass index; CK-MB: creatine kinase MB; cTnI: cardiac troponin I; DM: diabetes mellitus; eGFR: estimated glomerular filtration rate; HbA1c: glycosylated hemoglobin; HDL-C: high-density lipoprotein cholesterol; Hs-CRP: high-sensitivity C-reactive protein; LAD: left anterior descending artery; LCX: left circumflex artery; LM: left main coronary artery; LVEF: left ventricular ejection fraction; MVD: multivessel disease; non-DM: patients without diabetes mellitus; PCI: percutaneous coronary intervention; RCA: right coronary artery; TC: total cholesterol; TG: triglyceride; TIMI: thrombolysis in myocardial infarction; WBC; white blood cell.