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. 2020 May 20;11(7):1934–1943. doi: 10.1111/1759-7714.13485

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© 2020 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Anlotinib induces apoptosis and cycle arrest in HCC827 GR cells. (a) and (b) Fluorescence‐activated cell sorting (FACS) analysis was performed to investigate the effects of anlotinib on the cell cycle and apoptosis in HCC827 GR cells ( G0/G1, G2/M, and S). (c) Western blot analysis was used to detect the effect of anlotinib on Caspase‐3 and Cyclin D1 expression in HCC827 GR cells. (*** P < 0.001).

Inline graphic — Anlotinib induces apoptosis and cycle arrest in HCC827 GR cells. (a) and (b) Fluorescence‐activated cell sorting (FACS) analysis was performed to investigate the effects of anlotinib on the cell cycle and apoptosis in HCC827 GR cells ( G0/G1, G2/M, and S). (c) Western blot analysis was used to detect the effect of anlotinib on Caspase‐3 and Cyclin D1 expression in HCC827 GR cells. (*** P < 0.001).