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. Author manuscript; available in PMC: 2021 Aug 28.
Published in final edited form as: Cancer Lett. 2020 May 19;486:18–28. doi: 10.1016/j.canlet.2020.05.004

Figure 2.

Figure 2.

Method of loading therapeutics in exosome. Exosomes isolated from certain cell types show antitumor effects with its endogenously loaded composition. Exosomes can also be equipped exogenously with therapeutic proteins, nucleic acids, and small molecules. Endogenous loading of exosomes is achieved using a plasmid vector based expression of protein as a fusion protein with the tetraspanin proteins.