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. 2019 Jul 9;15(3):273–291. doi: 10.1016/j.ajps.2019.05.004

Table 1.

Advantages of microsponge based delivery systems

Sr. No. Advantages Ref.
1. Shelf-life and product stability can be prolonged without using preservatives, since bacteria are too large to enter into the microsponge [26]
2. Highly compartmentalized nature of microsponges results in very high internal surface area hence, they exhibit high pay loading capacity [27]
3. Undesirable properties like oiliness and tackiness, or undesirable feel or odor of ingredients can be considerably reduced which makes them suitable for topical delivery to skin [28]
4. Liquids can be transformed into free flowing powder, providing material handling benefits [28]
5. Microsponges help in improving elegance of the formulation [29]
6. MDS augment the efficacy of topically active agents and enables their sustained release [30]
7. Microsponges consist of interconnecting voids within a non-collapsible structure, with large porous surface [31]
8. Stable over a wide pH range of 1–11 and up to a temperature of 130 °C [32]