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. 2019 Feb 14;15(3):336–346. doi: 10.1016/j.ajps.2018.11.009

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© 2019 Shenyang Pharmaceutical University. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure Fig. 3. — Changes in droplet size (A and B) and zeta potential (C and D) of oil phase of self-microemulsifying drug delivery systems (200 mg) evaluated for 24 h after dilution of the formulations in distilled water (25 mL). Fig. 3(a) and (c) present changes in original values of the droplet size and zeta potential, and Fig. 3(b) and (d) show percentile changes in the droplet size and zeta potential. A, B, and C indicate the self-microemulsifying drug delivery system formulations consisting of Capryol™ 90, Labrasol®, and propylene glycol at three different weight ratios of 20:40:40, 20:53:27, and 20:60:20, respectively. Asterisk (*) indicates a statistical significance of P < 0.05.