Table 2.

Physicochemical characteristics of chitosan nanoparticles and lactose-PEG3000 microparticles.

(a) Physicochemical characteristics of chitosan nanoparticles
	F1	F2	F3	F4	F5	F6
Z-average size (nm)	610.03 ± 29.97	684.00 ± 17.61	275.67 ± 15.22	465.17 ± 58.74	338.70 ± 7.50	347.27 ± 19.39
Zeta potential (mV)	27.47 ± 1.87	27.86 ± 1.27	13.60 ± 2.36	13.10 ± 1.49	14.47 ± 0.23	20.17 ± 2.62
Polydispersity index	0.63 ± 0.12	0.57 ± 0.01	0.58 ± 0.01	0.80± 0.21	0.81 ± 0.12	0.42 ± 0.05
Circularity	0.90 ± 0.21	0.90 ± 0.23	0.82 ± 0.28	0.82 ± 0.26	0.87 ± 0.23	0.88 ± 0.23
Roughness (nm)	0.208 ± 0.004	0.379 ± 0.008	0.249 ± 0.004	0.301 ± 0.001	0.184 ± 0.003	0.211 ± 0.001
Crystallinity (%)	24.71 ± 1.85	19.40 ± 2.23	25.34 ± 0.69	27.02 ± 1.59	18.56 ± 1.01	18.72 ± 2.12
(b) Physicochemical characteristics of lactose-PEG3000 microparticles
d10 (µm)	1.58  ± 0.01	Circularity	0.16 ± 0.06	Tapped density (g/cm3)		0.2125 ± 0.0038
d50 (µm)	5.43 ± 0.10	Roughness (nm)	127.21 ± 1.11	Carr's index (%)		51.91 ± 0.13
d90 (µm)	54.60 ± 1.7	Bulk density (g/cm3)	0.1022 ± 0.0018	Hausner ratio		2.08 ± 0.01