Table 1b.
Model input parameters – Hospital stay and Costs (£, UK 2018).
| Base case | Range* | Distributionγ | Sources | |
|---|---|---|---|---|
| Cost of FMT - NGT | £740.16 | £592-£888 | Gamma (100,0.13) | Table 2 |
| Cost of FMT – Colposcopy | £3006.17 | £2405-£3607 | Gamma (100,0.03) | Table 2 |
| Cost of oral Vancomycin 250 mga | £200.11 | £160-£240 | Gamma (100,0.48) | [29] |
| Cost of oral Vancomycin 500 mgb | £400.23 | £320-£480 | Gamma (100,0.24) | [29] |
| Cost of oral Vancomycin TPc | £297.60 | £238-£358 | Gamma (100,0.34) | [29] |
| Cost of Fidaxomicin d | £1350.00 | £1080-£1620 | Gamma (100,0.07) | [29] |
| Cost of hospital stay per day e | £404 | £323-£485 | Gamma (100,0.25) | [32] |
| Hospital stay – FMT (days) | 5 | 2–20 | Fixed | [10] |
| Hospital stay – Antibiotics (days) | 10 | 6–27 | Fixed | [10] |
Abbreviations: FMT, Feacal Microbiota Transplant; NGT, Nasogastric Tube, TP, Taper Pulsed.
γ
Probabilistic sensitivity analysis, alpha and lambda values for Gamma distribution.
a
Cost of vancomycin 250 mg, 4 times a day for 10 days.
b
Cost of Vancomycin 500 mg, 4 times a day for 10 days.
c
Cost of Vancomycin pulse taper for 6 weeks starting with 250 mg.
d
Cost of Fidaxomicin 200 mg for 10 days.
e
Inpatient, specialist palliative care (adults only), average cost per bed day.
⁎
Cost range was based on assumption - varying the base value by +/−20%.