Weighted β-diversity analysis of fungal communities in 1-year-old mice after antibiotic perturbation. PCoA of fecal fungal composition across time (days 0, 14, 21, 71, 86) in 1-year-old (A) WT and (B) Nod2-KO mice, and (C) combined data for both genotypes only at day 0 (pretreatment) and day 86. (D) Nonparametric analysis of variance (PERMANOVA) on Bray–Curtis distance in relation to genotype and fungal community composition. Pseudo F, Pseudo F ratio as calculated by PERMANOVA. Larger F-ratios indicate more pronounced group separation.