Table 2.
Cox regression analysis of CHMP4C as a predictor of prognosis of CC. CI, confidence interval; HR, hazard ratio; M, metastasis; N, regional lymph node; T, tumor.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| P‐value | HR | 95% CI | P‐value | HR | 95% CI | |
| CHMP4C expression（low/high） | 0.041* | 1.638 | 1.021–2.628 | 0.260 | 1.800 | 0.647–5.013 |
| Clinical stage（I + II/III + IV） | 0.001* | 2.286 | 1.397–3.743 | 0.215 | 0.332 | 0.058–1.895 |
| Pathologic T (T1 + T2/T3 + T4) | 0.000* | 3.613 | 1.907–6.846 | 0.015* | 6.442 | 1.434–28.930 |
| Pathologic M (M0/M1) | 0.020* | 3.671 | 1.229–10.962 | 0.989 | 0.000 | 0.000 |
| Pathologic N (N0/N1 + N2 + N3) | 0.003* | 2.807 | 1.408–5.593 | 0.77 | 2.545 | 0.904–7.168 |
| Age (<60/≥60 years） | 0.054 | 1.641 | 0.991–2.715 | |||
| Grade (G1 + G2/G3 + G4) | 0.681 | 0.896 | 0.530–1.513 | |||
*
P < 0.05.